| Employer Description Guillermo J. Tearney, M.D., Ph.D. Tearney Lab – Wellman Center for Photomedicine Massachusetts General Hospital Job Description A Postdoctoral research fellowship in the area of optical coherence tomography (OCT) is available in the Tearney Lab (www.tearneylab.org) at the Massachusetts General Hospital (MGH) in the Wellman Center for Photomedicine. This appointment will be made at the rank of postdoctoral fellow or instructor at Harvard Medical School, commensurate with the applicant’s experience. MGH’s role as a leading teaching affiliate of Harvard Medical School and close ties to Harvard University and MIT provide an outstanding environment for developing and translating new OCT technologies with applications in basic and clinical research. The fellowship will focus on high resolution OCT imaging devices, including development of novel optical techniques, engineering of in vivo endoscopic probes, and translation to clinical use. Current medical applications of micro-OCT include imaging of mucociliary clearance to monitor treatment response in pulmonary disorders such as cystic fibrosis, high-resolution imaging of coronary artery disease, and diagnosis of early cancer. The ideal candidate for this position is an organized and creative problem-solver experienced with advanced optics, biomedical engineering, computational methods, and image analysis, as well as capable of leading a multidisciplinary research team. Representative recent publications from our group include: - Leung, H.M., et al. Imaging intracellular motion with dynamic micro-optical coherence tomography. Biomed Opt Express 11, 2768-2778 (2020).
- Yin, B., et al. 3D cellular-resolution imaging in arteries using few-mode interferometry. Nature: Light Sci Appl 8, 104 (2019).
- Leung, H.M., et al. Intranasal micro-optical coherence tomography imaging for cystic fibrosis studies. Sci Transl Med 11(2019).
- Gora, M.J., et al. Tethered capsule endomicroscopy for microscopic imaging of the esophagus, stomach, and duodenum without sedation in humans (with video). Gastrointest Endosc 88, 830-840 e833 (2018).
- Gerbaud, E., et al. Plaque burden can be assessed using intravascular optical coherence tomography and a dedicated automated processing algorithm: a comparison study with intravascular ultrasound. Eur Heart J Cardiovasc Imaging 21, 640-652 (2020).
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